Serveur d'exploration MERS

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Burden of Middle East respiratory syndrome coronavirus infection in Saudi Arabia

Identifieur interne : 000673 ( Main/Exploration ); précédent : 000672; suivant : 000674

Burden of Middle East respiratory syndrome coronavirus infection in Saudi Arabia

Auteurs : Rajaa M. Al-Raddadi [Arabie saoudite] ; Omaima I. Shabouni [Arabie saoudite] ; Zeyad M. Alraddadi [Arabie saoudite] ; Abdulmohsen H. Alzalabani [Arabie saoudite] ; Ahmad M. Al-Asmari [Arabie saoudite] ; Adel Ibrahim [Arabie saoudite] ; Abdullatif Almarashi [Arabie saoudite] ; Tariq A. Madani [Arabie saoudite]

Source :

RBID : PMC:7102537

Abstract

MERS-coronavirus infection is currently responsible for considerable morbidity and mortality in Saudi Arabia. Understanding its burden, as an emerging infectious disease, is vital for devising appropriate control strategies. In this study, the burden of MERS-CoV was estimated over 31 months period from June 6, 2012 to January 5, 2015. The total number of patients was 835; 528 (63.2%) patients were male, 771 (92.3%) patients were ≥25 years of age, and 210 (25.1%) patients were healthcare workers. A total of 751 (89.9%) patients required hospitalization. The median duration between onset of illness and hospitalization was 2 days (interquartile range, 0–5). The median length of hospital stay was 14 days (IQR, 6–27). The overall case fatality rate was 43.1%. Basic reproductive number was 0.9. Being Saudi, non-healthcare workers, and age ≥65 years were significantly associated with higher mortality. In conclusion, MERS-CoV infection caused a substantial health burden in Saudi Arabia.


Url:
DOI: 10.1016/j.jiph.2019.11.016
PubMed: 31843650
PubMed Central: 7102537


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<p>MERS-coronavirus infection is currently responsible for considerable morbidity and mortality in Saudi Arabia. Understanding its burden, as an emerging infectious disease, is vital for devising appropriate control strategies. In this study, the burden of MERS-CoV was estimated over 31 months period from June 6, 2012 to January 5, 2015. The total number of patients was 835; 528 (63.2%) patients were male, 771 (92.3%) patients were ≥25 years of age, and 210 (25.1%) patients were healthcare workers. A total of 751 (89.9%) patients required hospitalization. The median duration between onset of illness and hospitalization was 2 days (interquartile range, 0–5). The median length of hospital stay was 14 days (IQR, 6–27). The overall case fatality rate was 43.1%. Basic reproductive number was 0.9. Being Saudi, non-healthcare workers, and age ≥65 years were significantly associated with higher mortality. In conclusion, MERS-CoV infection caused a substantial health burden in Saudi Arabia.</p>
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<li>Arabie saoudite</li>
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</record>

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